In addition to the drones, 20 missiles of various types were launched at various parts of Ukraine, according to the air force, which said the barrage mainly targeted central and western areas of Ukraine.
Ukraine's air defenses destroyed 277 drones and 19 missiles during the flight, an air force statement said, claiming that only 10 drones or missiles reached their target, according to AP.
It was not possible to independently verify the claim.
Russia's airstrikes usually begin late at night and end in the morning, as drones are harder to spot in the dark.
Russia has relentlessly targeted civilian areas in Ukraine with Shahed drones during the more than three-year war. The attacks have killed more than 12,000 Ukrainian civilians, according to the United Nations.
Russia says it is only targeting military targets.
At least one person was injured in Rivne, a city located far from the front line in northwestern Ukraine.
The massive attack came shortly after Russia launched 452 drones and 45 missiles into Ukraine on the night of June 6, one of the largest airstrikes of the full-scale war. The Kremlin said the bombing was in retaliation for Kiev's"Operation Spider Web," in which Russian strategic aircraft were targeted with drones.